INSTITUT DES SCIENCES ANALYTIQUES (ISA)

The Institute for Analytical Sciences (ISA) brings together more than 130 scientists & technical staff with a range of expertise from theoretical chemistry through biochemistry, analytical chemistry, electrochemistry to physics. ISA has cutting-edge instrumentation. Research focuses on the development of new methods for the analysis of challenging systems applied to health and the environment. ISA is involved in both initial (eg. Euromaster in analytical chemistry) and continuing training (CNRS formation entreprises, Focal Lyon1). ISA participates in technology transfer (patents, start-ups) and committees of national and European organizations for standardization.

• Methods, data analysis, miniaturization.
• Environment : micropollutants, biomarkers, biosensors, exposome, biosourcedproducts.
• Health : biomarkers, diagnostic.

Multidimensions for complex samples : HRMS & hyphenated methods, SCOUT MRM3, SPE-LC- MS/MSonline, micro-QuEChERS, nano-LC-MS/ MS, nanoLC-HRMS..., ionic mobility, multidimensional chromatography, UHPLC, CPC, 2DLC-HRMS, speciation (LC2D-ICP-MS), spectroscopy (LA-ICP-MS, LIBS...), elemental & isotopic analysis (EA-C/P-IRMS, GC- C/P-IRMS, LC-IRMS). Experimental & theoretical approaches for molecular interactions: fragments screening, NMR, SANS, SAXS, molecular modelisation, DFT, post-HF, chemiometrics, clusters of CPU’s and GPU servers, molecular dynamics and interactions, proteins. Surface and miniaturization for analytical research and technology: biosensors, biosensors network, microfluidic systems, controlled nanostructuration and controlled (multi)functionalization of surfaces, separtive microsystems, development of stationary phases, characterization (TOF-SIMS, SEM-EDS, XPS, ATG, IR).